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Publications

2021

McCann JL, Cristini A, Law EK, Lee SY, Tellier M, Carpenter MA, Beghè C, Kim JJ, Jarvis MC, Stefanovska B, Temiz NA, Bergstrom EN, Salamango DJ, Brown MR, Murphy S, Alexandrov LB, Miller KM, Gromak N, Harris RS. R-loop homeostasis and cancer mutagenesis promoted by the DNA cytosine deaminase APOBEC3B. bioRxiv, 2021

Tellier M, Zabrowoska J, Neve J, Nojima T, Hester S, Furger A, Murphy S. CDK9 and PP2A regulate the link between RNA polymerase II transcription termination and RNA maturation. bioRxiv, 2021

Isa NF, Bensaude O, Aziz NC, Murphy S. HSV-1 ICP22 is a selective viral repressor of cellular RNA polymerase II-mediated transcription elongation. Vaccines, 2021

Prokhorova E, Agnew T, Wondisford AR, Tellier M, Kaminski N, Beijer D, Holder J, Groslambert J, Suskiewicz MJ, Zhu K, Reber JM, Krassnig SC, Palazzo L, Murphy S, Nielsen ML, Mangerich A, Ahel D, Baets J, O’Sullivan RJ, Ahel I. Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease. Molecular Cell, 2021.

Studniarek C, Tellier M, Martin PGP, Murphy S, Kiss T, Egloff S. The 7SK/P-TEFb snRNP controls ultraviolet radiation-induced transcriptional reprogramming. Cell Reports, 2021.

2020

Studniarek C, Egloff S, Murphy S. Noncoding RNAs set the stage for RNA polymerase II transcription. Trends in Genetics, 2020.

Tellier M, Murphy S. Incomplete removal of ribosomal RNA can affect chromatin RNA-seq data analysis. Transcription, 2020.

Tellier M, Zaborowska J, Caizzi L, Mohammad E, Velychko T, Schwalb B, Ferrer-Vicens I, Blears D, Nojima, T, Cramer P, Murphy S. CDK12 globally promotes RNA polymerase II transcription elongation and carboxyl-terminal domain phosphorylation. Nucleic Acids Research, 2020.

Tellier M, Maudin I, Murphy S. Transcription and splicing: a two-way street. WIREs RNA, 2020

2019

Tellier M, Hardy JG, Norbury CJ, Murphy SEffect of CFIm68 knockdown on RNA polymerase II transcription. BMC Research Notes, 2019.

2018

Tellier M, Hardy JG, Norbury CJ, Murphy SEffect of CFIm25 knockout on RNA polymerase II transcription. BMC Research Notes, 2018.

Nojima T*,**, Tellier M*, Foxwell J, Rebeiro de Almeida C, Tan Wong SM, Dhir S, Dujardin G, Dhir A, Murphy S**, Proudfoot NJ**. Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence. Molecular Cell, 2018.

Bauer, DLV., Tellier, M., Martinez-Alonso, M., Nojima, T., Proudfoot, NJ, Murphy, S. and Fodor, E. Influenza Virus Mounts a Two-Pronged Attack on Host RNA Polymerase II Transcription. Cell Reports, 2018.

Wood, K.; Tellier, M.; Murphy, SDOT1L and H3K79 Methylation in Transcription and Genomic StabilityBiomolecules, 2018.

2017

Egloff, S., Vitali, P., Tellier, M., Raffel, R., Murphy, S. and Kiss, T. The 7SK snRNP associates with the little elongation complex to promote snRNA gene expression. The EMBO Journal, 2017.

Guiro, J., & Murphy, S. Regulation of expression of human RNA polymerase II-transcribed snRNA genes. Open biology, 2017.

Hardy JG, Tellier M, Murphy S, Norbury CJ. The RS Domain of Human CFIm68 Plays a Key Role in Selection Between Alternative Sites of Pre-mRNA Cleavage and Polyadenylation. bioRxiv, 2017.

2016

Vazquez-Arango, P., Vowles, J., Browne, C., Hartfield, E., Fernandes, H.J., Mandefro, B., Sareen, D., James, W., Wade-Martins, R., Cowley, S.A., Murphy, S. and O'Reilly, D. Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease. Nucleic Acids Research, 2016.

Zaborowska, J., Egloff, S. and Murphy, S. The pol II CTD: new twists in the tail. Nature Structural & Molecular Biology, 2016.

Zaborowska, J., Isa, N.F. and Murphy, S. P‐TEFb goes viral. BioEssays, 2016.

Tellier, M., Ferrer-Vicens, I. and Murphy, S. The point of no return: The poly (A)-associated elongation checkpoint. RNA biology, 2016.

2015

Kelly, S., Georgomanolis, T., Zirkel, A., Diermeier, S., O'Reilly, D., Murphy, S., Längst, G., Cook, P.R. and Papantonis, A. Splicing of many human genes involves sites embedded within introns. Nucleic acids research, 2015.

Laitem, C., Zaborowska, J., Isa, N.F., Kufs, J., Dienstbier, M. and Murphy, S. CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II–transcribed genes. Nature structural & molecular biology, 2015.

Laitem, C., Zaborowska, J., Tellier, M., Yamaguchi, Y., Cao, Q., Egloff, S., Handa, H. and Murphy, S. CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription. Transcription, 2015.